Email this article Prediction of phenotype R5/X4 of HIV-1 variants circulating in Russia, by using computer methods
- Issue: Vol 54, No 3 (2009)
- Pages: 17-20
- Section: Articles
- URL: https://virusjour.crie.ru/jour/article/view/11908
- ID: 11908
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Abstract
The paper presents the data of a comparative analysis of various bioinformation methods for evaluating the tropism of HIV-1 subtype A that is typical of Russia. The prevalence of CXCR4- and CCR5-tropic viruses among the variants prevailing in Russia was studied using the B-PSSM (sinsi) prediction method. No X4-tropic variants were found among 124 samples of HIV-1 isolated from the Russian patients not receiving antiretrovirus therapy.
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).