PCR study of the human herpes virus type 6 and other viruses of the herpes group in eye diseases

O. S. Slepowa; Слепова О. С.; E. V. Svetlova; Светлова Е. В.; L. A. Kovaleva; Ковалева Л. А.; P. V. Makarov; Макаров П. В.; A. E. Kugusheva; Кугушева А. Э.; E. V. Denisova; Денисова Е. В.; E. S. Vahova; Вахова Е. С.; G. Yu. Zaharova; Захарова Г. Ю.; Yu. A. Kondrat’eva; Кондратьева Ю. А.; A. E. Andryushin; Андрюшин А. Е.; V. V. Demkin; Демкин В. В.

PCR study of the human herpes virus type 6 and other viruses of the herpes group in eye diseases

Authors: Slepowa O.S.¹, Svetlova E.V.¹, Kovaleva L.A.¹, Makarov P.V.¹, Kugusheva A.E.¹, Denisova E.V.¹, Vahova E.S.¹, Zaharova G.Y.¹, Kondrat’eva Y.A.¹, Andryushin A.E.¹, Demkin V.V.²
Affiliations:
1. Moscow Helmholtz Research Institute of Eye Diseases
2. Institute of Molecular Genetics, Russian Academy of Sciences
Issue: Vol 60, No 6 (2015)
Pages: 45-48
Section: TO VIROLOGIST’S AID
URL: https://virusjour.crie.ru/jour/article/view/380
ID: 380

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Abstract

To study the role of the HHV-6 type in the development of eye diseases PCR tests of blood (152), cornea biopsies (61), and intraocular fluids (11) for HHV-6 and other viruses of the herpes group (HSV type 1 and 2, CMV, EBV) were conducted. It was found that the HHV-6, along with other representatives of the Herpesviridae, can be detected in patients with different clinical forms of ophthalmopathology (174 patients were surveyed). Viral DNA was detected in blood, cornea, and in the anterior chamber fluid. The obtained data allow that the HHV-6 to be suggested as a possible cause of the ophthalmic herpes along with the other viruses of this group. It makes finding the virus DNA an essential step towards setting the etiologic diagnosis of the ophthalmological patients.

Keywords

human herpes virus type 6, eye diseases, cornea, blood, polymerase chain reaction

About the authors

O. S. Slepowa

Moscow Helmholtz Research Institute of Eye Diseases

Author for correspondence.
Email: slepowaolga@yandex.ru

Ol’ga Slepova, , MD,PhD, ScD, prof.

105062, Moscow

Russian Federation

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PCR study of the human herpes virus type 6 and other viruses of the herpes group in eye diseases

Full Text

Abstract

Keywords

About the authors

References

Supplementary files

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