Hepatitis C virus: variability mechanisms, classification, evolution

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Abstract

Hepatitis c virus (HCV) is one of the most dynamically evolving viral pathogens. In the last decade extensive molecular epidemiological studies demonstrated great HCV diversity. This review describes the HCV variability mechanisms and the current HCV classification, presents data on the geographical spread of different HCV subtypes and its evolution, including natural recombinant forms.

About the authors

O. V. Kalinina

St. Petersburg Pasteur Institute

Author for correspondence.
Email: olgakalinina@mail.ru

Ol’ga Kalinina, MD, PhD, ScD

St. Petersburg

Russian Federation

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