Email this article Evolution ofthe receptor specificity of influenza viruses hemagglutinin in its transfer from duck to pig and man
- Issue: Vol 49, No 3 (2004)
- Pages: 25-31
- Section: Articles
- Submitted: 09.06.2023
- Published: 15.06.2004
- URL: https://virusjour.crie.ru/jour/article/view/11846
- ID: 11846
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Abstract
The receptor properties of Н1 and H2 influenza viruses (IV), isolated from duck, pig and man were studied by using
the natural and synthetic sialoglycoconjugates. It was shown that viruses, isolated from different hosts, adapt
themselves to the host cell receptors. The IV affinity was increasing to 6'sialy(N-acetyllactosamine) in proportion
as amino acids (in positions 138,190,194 and 225), which are for avian IV, were increasingly replacing. Some of
the porcine viruses display adaptation to the human receptor, i.e. 6'sialy (N-acety llactosamine), however, all tested
porcine influenza viruses, belonging to different evolution branches, acquired even more affinity to sulphated and
fucozyled derivatives of 3'sialy(N-acetyllactosamine) - (Neu5ACa2-3gALpi-4(fUCa1-3)(6-sulfo)GlcNAcp).
the natural and synthetic sialoglycoconjugates. It was shown that viruses, isolated from different hosts, adapt
themselves to the host cell receptors. The IV affinity was increasing to 6'sialy(N-acetyllactosamine) in proportion
as amino acids (in positions 138,190,194 and 225), which are for avian IV, were increasingly replacing. Some of
the porcine viruses display adaptation to the human receptor, i.e. 6'sialy (N-acety llactosamine), however, all tested
porcine influenza viruses, belonging to different evolution branches, acquired even more affinity to sulphated and
fucozyled derivatives of 3'sialy(N-acetyllactosamine) - (Neu5ACa2-3gALpi-4(fUCa1-3)(6-sulfo)GlcNAcp).
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References
- Чувакова 3. К., Беклемишев А. Б., Назарова Л. М. и др. Анализ аминокислотной последовательности тяжелой субъединицы гемагглютинина вируса гриппа А/Алма-Ата/1417/ 84 // Молекул, биол. - 1994. - № 28. - С. 30-34.
- Bavin N., Gambaryan A., Matrosovich M. et al. Early alterations of the receptor-binding properties of HI, H2, and H3 avian influenza virus hemagglutinins after their introduction into mammals// J. Virol. - 2000. - Vol. 74. - P. 8502-8512.
- Brown I. H. The epidemiology and evolution of influenza viruses in pigs // Vet. Microbiol. - 2000. - Vol. 74. - P. 29-46.
- Connor R. J., Kawaoka Y., Webster R. G., Paulson J. С. Receptor specificity in human, avian, and equine H2 and H3 influenza virus isolates // Virology. - 1994. - Vol. 205. - P. 17-23.
- Couceiro J. N. S. S., Paulson J. C, Baum L. G. Influenza virus strains electively recognize sialyloligosaccharides on human respiratory epithelium: the role of the host cell in selection of hemagglutinin receptor specificity // Virus Res. - 1993. - Vol. 29. - P. 155-165.
- Gambaryan A. S., Marinina V. P., Tuzikov A. B. et al. Effects of host-dependent glycosylation of hemagglutinin on receptorbinding properties of H1N1 human influenza A virus grown in MDCK cells and in embryonated eggs // Virology. - 1998. - Vol. 247. - P. 170-177.
- Guo Y, Li J., Cheng X. et al. Discovery of humans infected by avian influenza A (H9N2) virus // Chin. J. Exp. Clin. Virol. - 1999. - Vol. 13. - P. 105-108.
- Но Т., Couceiro J. N., Kelm S. et al. Molecular basis for the generation in pigs of influenza A viruses with pandemic potential //J. Virol. -1998. - Vol. 72. - P. 7367-7373.
- Kida H., Ho Т., Yasuda J. et al. Potential for transmission of avian influenza viruses to pigs // J. Gen. Virol. - 1994. - Vol. 75. - P. 2183-2188.
- Ludwig S., Stitz L., Planz O. et al. European swine virus as a possible source for the next influenza pandemic? // Virology. - 1995. - Vol. 212. - P. 555-561.
- Matrosovich M. N., Gambaryan A. S., Tuzikov A. B. et al. Probing of the receptor-binding sites of the HI and H3 influenza A and influenza В virus hemagglutinins by synthetic and natural sialosides // Virology. - 1993. - Vol. 196. - P. 111-121.
- Paulson J. С Interactions of animal viruses with cell surface receptors // The Receptors / Ed. M. Conn. - Orlando, 1985. - Vol. 2 . - P . 131-219.
- Rimmelzwaan G. F., de Jong J. C., Bestebroer Т. М. et al. Antigenic and genetic characterization of swine influenza A (H1N1) viruses isolated from pneumonia patients in The Netherlands // Virology. - 2001. - Vol. 282. - P. 301-306.
- Rogers G. N., D'Souza B. L. Receptor-binding properties of human and animal HI influenza virus isolates // Virology. - 1989. - Vol. 173. - P. 317-322.
- Sauter N. K., Hanson J. E., Glick G. D. et al. Binding of influenza virus hemagglutinin to analogs of its cell-surface receptor, sialic acid: analysis by proton nuclear magnetic resonance spectroscopy and X-ray crystallography // Biochemistry. - 1992. - . Vol. 31. - P. 9609-9621.
- Stech J., Xiong X., Scholtissek C., Webster R. G. Independence of evolutionary and mutational rates after transmission of avian influenza viruses to swine // J. Virol. - 1999. - Vol. 73. - P. 1878-1884.
- Suzuki Т., Horiike G., Yamazaki Y. et al. Swine influenza virus strains recognize sialylsugar chains containing the molecular species of sialic acid predominantly present in the swine tracheal epithelium // FEBS Lett. - 1997. - Vol. 404. - P. 192-196.
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).