Detection of the intrahospital and laboratory contamination with the hepatitis A and C viruses

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Abstract

Detection and confirmation of nosocomial viral contamination is an important aspect of the laboratory diagnostics. Sensitive methods were used to detect contamination of hospital and laboratory environment with the hepatitis A (HAV) and hepatitis C (HCV) viruses. One case of the contamination with HAV RNA was detected in hospital environment. There are multiple cases of the contamination with HCV RNA (21.1%) and cDNA (78.9%) in the laboratory environment.

About the authors

S. A. Esper

Peoples’ Friendship University of Russia

Author for correspondence.
Email: suzan_asper@yahoo.com

Suzan Esper, postgraduate

Moscow

Russian Federation

T. V. Grebennikova

Peoples’ Friendship University of Russia; D.I. Ivanovsky Institute of Virology «Federal Research Centre for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»

Email: fake@neicon.ru
Moscow Russian Federation

M. G. Isaguliants

D.I. Ivanovsky Institute of Virology «Federal Research Centre for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»

Email: fake@neicon.ru
Moscow Russian Federation

K. K. Kyuregyan

M.P. Chumakov Institute of Poliomyelitis and Viral Encephalitides

Email: fake@neicon.ru
Moscow Russian Federation

A. G. Prilipov

D.I. Ivanovsky Institute of Virology «Federal Research Centre for Epidemiology and Microbiology named after the honorary academician N.F. Gamaleya»

Email: fake@neicon.ru
Moscow Russian Federation

A. M. Hodorovich

Peoples’ Friendship University of Russia

Email: fake@neicon.ru
Moscow Russian Federation

References

  1. Шаханина И.Л., Радуто О.И. Вирусные гепатиты в России: официальная статистика и экономические потери. Вакцинация. Новости вакцинопрофилактики. 2001; 6: 6–9.
  2. Онищенко Г.Г., Актуальные вопросы эпидемиологии и профилактики вирусных гепатитов В и С в Российской Федерации. Медицина для всех. 1999; 2: 2–4.
  3. Ganime A.C., Carvalho-Costa F.A., Mendonça M.C.L., Vieira C.B., Santos M., Filho R.C. et al. Group A rotavirus detection on environmental surfaces in a hospital intensive care unit. Am. J. Infect. Control. 2012; 40 (6): 544–7.
  4. Carducci A., Verani M., Lombardi R., Casini B., Privitera G. Environmental survey to assess viral contamination of air and surfaces in hospital settings. J. Hosp. Infect. 2011; 77 (3): 242–7.
  5. Davanzo E., Frasson C., Morandin M., Trevisan A. Occupational blood and body fluid exposure of university health care workers. Am. J. Infect. Control. 2008; 36 (10): 753–6.
  6. Petersen N.J. An assessment of the airborne route in hepatitis B transmission. Ann. N Y Acad. Sci.1980; 353: 157–66.
  7. lopman B.A., Reacher M.H., Vipond I.B., Hill D., Perry C., Halladay T. et al. Epidemiology and cost of nosocomial gastroenteritis, Avon, England, 2002–2003. Emerg. Infect. Dis. 2004; 10 (10): 1827–34.
  8. Gupta A.K., Anand N.K., Manmohan N.K., Lamba L.M.S., Gupta R., Srivastava L. Role of bacteriological monitoring of the hospital environment and medical equipment in a neonatal intensive care unit. J. Hosp. Infect.1991; 19: 263–71.
  9. Gallimore C.I., Taylor C., Gennery A.R., Cant A.J., Galloway A., Xerry J. et al. Comparison of two pediatric wards over a winter season. J. Clin. Microbiol. 2008; 46: 3112–5.
  10. Morris J., Duckworth G.J., Ridgway G.L. Gastrointestinal endoscopy decontamination failure and the risk of transmission of blood-borne viruses: a review. J. Hosp. Infect. 2006; 63: 1–13.
  11. Morter S., Bennet G., Fish J., Richards J., Allen D.J., Nawaz S. et al. Norovirus in the hospital setting: virus introduction and spread within the hospital environment. J. Hosp. Infect. 2011; 77: 106–12.
  12. Chadwick P.R., Beards G., Brown D., Caul E.O., Cheesbrough J., Clarke I. et al. Management of hospital outbreaks of gastroenteri- tis due to small round structured viruses. J. Hosp. Infect. 2000; 45: 1–10.
  13. Harris J.P., Lopman B.A., O’Brien S.J. Infection control measures for norovirus: a systematic review of outbreaks in semi-closed settings. J. Hosp. Infect. 2010; 74: 1–9.
  14. Xerry J., Gallimore C.I., Iturriza-Gómara M., Allen D.J., Gray J.J. Transmission events within outbreaks of gastroenteritis determined through analysis of nucleotide sequences of the P2 domain of genogroup II noroviruses. J. Clin. Microbiol. 2008; 46 (3): 947–53.
  15. Pang X.L., Lee B.E., Pabbaraju K., Gabos S., Craik S., Payment P. et al. Pre-analytical and analytical procedures for the detection of enteric viruses and enterovirus in water samples. J. Virol. Methods. 2012; 184: 77–83.
  16. Reynolds K.A., Gerba C.P., Pepper I.L. Detection of infectious enteroviruses by an integrated cell culture-PCR procedure. Appl. Environ. Microbiol. 1996; 62 (4): 1424–7.
  17. Эспер С.А., Гребенникова Т.В., Исагулянц М.Г., Кюрегян К.К., Ходорович А.М. Разработка методов и подходов обнаружения вирусов гепатита А и С на поверхностях для дальнейшего исследования внутрибольничной контаминации. Здоровье населения и среда обитания. 2015; 3 (264): 42–4.

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Copyright (c) 2015 Esper S.A., Grebennikova T.V., Isaguliants M.G., Kyuregyan K.K., Prilipov A.G., Hodorovich A.M.

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