Experimental interspecies transmission of the bovine leukaemia virus

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Abstract

Interspecies transmission of the BLV by the inoculation of milk and blood of cows infected by the enzootic bovine leukosis directly into the bloodstream or through the gastrointestinal tract of heterologous species (rabbit) was demonstrated. The results of this work indicate the ability of the BLV to overcome the interspecies barriers. Use of native milk with infectious properties is shown to be dangerous.

About the authors

M. I. Gulyukin

Y.R. Kovalenko All-Russian Institute of Experimental Veterinary Medicine

Author for correspondence.
Email: admin@viev.ru

Mikhail Gulyukin, Doctor of Veterinary Sciences, prof., academician of RAS

Moscow

Россия

N. G. Kozyreva

Y.R. Kovalenko All-Russian Institute of Experimental Veterinary Medicine

Email: fake@neicon.ru
Moscow Россия

L. A. Ivanova

Y.R. Kovalenko All-Russian Institute of Experimental Veterinary Medicine

Email: fake@neicon.ru
Moscow Россия

T. V. Stepanova

Y.R. Kovalenko All-Russian Institute of Experimental Veterinary Medicine

Email: fake@neicon.ru
Moscow Россия

A. I. Klimenko

North-Caucasus Zonal Scientific Research Veterinary Institute

Email: fake@neicon.ru
Novocherkassk Россия

A. V. Kovalenko

North-Caucasus Zonal Scientific Research Veterinary Institute

Email: fake@neicon.ru
Novocherkassk Россия

Y. D. Drobin

North-Caucasus Zonal Scientific Research Veterinary Institute

Email: fake@neicon.ru
Novocherkassk Россия

V. N. Vasilenko

North-Caucasus Zonal Scientific Research Veterinary Institute

Email: fake@neicon.ru
Novocherkassk Россия

References

  1. Stoye J.P., Blomberg J., Coffin J.M., Fan H. et al. Retroviridae. In: King A.M.Q., Adams M.J., Carstens E.B., Lefkowitz E.J., eds. Virus Taxonomy. 9th Rep. Intern. Comm. Taxonomy of Viruses. London, Waltham, San Diego: Elsevier Ac. Press.; 2012: 481–95.
  2. World Organization of Animal Health (OIE). Enzootic bovine leucosis. In: Manual of standarts for diagnostic tests and vaccines. 2008; 2: 729–38.
  3. Burny A., Bruck C., Cleuter V., Couez D., Deschamps J., Ghysdael J. et al. A bovine leukemia virus, a versatile agent with various pathogenic effects in various animal species. Cancer Res. 1985, 45 (9, suppl.): 4578–82.
  4. Dimitrov P., Simeonov K., Todorova K., Ivanova Z., Toshkova R., Shikova E. et al. Pathological features of experimental bovine leukaemia viral (BLV) infection in rats and rabbits. Bull. Vet. Inst. Pulawy. 2012; 56: 115–20.
  5. Hirsch V.M., Dapolito G., Goeken R., Campbell B.J. Phylogeny and natural history of the primate lentiviruses, SIV and HIV. Curr. Opin. Genet. Dev. 1995; 5: 798–806.
  6. Wolfe N.D., Heneine W., Carr J.K., Garcia A.D., Shanmugam V., Tamoufe U. et al. Emergence of unique primate T-lymphotropic viruses among central African bushmeat hunters. Proc. Natl. Acad. Sci. U S A. 2005; 102 (22): 7994–9.
  7. Валихов А.Ф., Бурба Л.Г., Шишков В.П. Иммунологическое и вирусологическое исследование молока, крови и спермы крупного рогатого скота, инфицированного онкорнавирусом. Лейкозы сельскохозяйственных животных. В кн.: Материалы Советско-Нидерландского симпозиума. Труды Всероссийского научно-исследовательского института экспериментальной ветеринарии им. Я.Р. Коваленко. М.; 1983; 59: 71–2.
  8. Buehring G.C., Kramme P.M., Schultz R.D. Evidence for bovine leukemia virus in mammary epithelial cells of infected cows. Lab. Invest. 1994; 71: 359–65.
  9. Buehring G.C., Choi K.Y., Jensen H.M. Bovine leukemia virus in human breast tissues. Breast Cancer Res. 2001; 3 (suppl. 1): S1–24.
  10. Dube S., Bachman S., Spicer T., Love J., Choi D., Esteban E. et al. Degenerate and specific PCR assays for the detection of bovine leukaemia virus and primate T cell leukaemia/lymphoma virus pol DNA and RNA: phylogenetic comparisons of amplified sequences from cattle and primates from around the world. J. Gen. Virol. 1997; 78: 1389–98.
  11. Buehring G.C., Philpott S.M., Choi K.Y. Humans Have Antibodies Reactive with Bovine Leukemia Virus. AIDS Res. Hum. Retrovirus. 2003; 19 (12): 1105–13.
  12. Mesa G., Ulloa J.C., Uribe A.M., Gutierrez M.F. Bovine Leukemia Virus Gene Segment Detected in Human Breast Tissue. Open J. Med. Microbiol. 2013; 3 (1): 84–90.
  13. Козырева Н.Г., Иванова Л.А., Гулюкин М.И., Колбасов Д.В., Цыбанов С.Ж., Калабеков И.М. и др. Оптимизация ПЦР для выявления ДНК провируса лейкоза КРС с использованием сконструированных праймеров, комплементарных участку провирусного гена pol. Ветеринария и кормление. 2011; 1: 16–7.
  14. Beier D., Blankenstein P., Marquardt O., Kuzmak J. Identification of different BLV provirus isolates by PCR, RFLPA and DNA sequencing. Berl. Munch. Tierarztl. Wochenschr. 2001; 114 (7–8): 252–6.
  15. Kato H., Koya Y., Ohashi T., Hanabuchi S., Takemura F., Fujii M. et al. Oral administration of human T-cell leukemia virus type 1 induces immune unresponsiveness with persistent infection in adult rats. J. Virol. 1998; 72 (9): 7289–93.
  16. Zhao T.-M., Hague V., Caudell D.L., Simpson R.M., Kindt T.J. Quantification of HTLV-I proviral load in experimentally infected rabbits. Retrovirology. 2005; 2: 34.

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Copyright (c) 2015 Gulyukin M.I., Kozyreva N.G., Ivanova L.A., Stepanova T.V., Klimenko A.I., Kovalenko A.V., Drobin Y.D., Vasilenko V.N.

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