Review of current issues of diagnosis and prevention of blood-borne nosocomial viral infections

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Abstract

Provision of infection security in transplantology and transfusiology is a challenging and significant problem that depends on the quality of medical donor selection and laboratory diagnosis of the blood collected. At present, a large number of blood-borne viruses are known; nevertheless, in Russia, the list of viral agents to be tested during the examination by the blood service boils down to three ones: HIV, hepatitis C and hepatitis B viruses.
The review article demonstrates the need for implementation of additional laboratory tests for the agents of the priority healthcare-associated blood-borne infections (HAI) using a risk-based approach, i.e., on specified sites and in high risk groups. It presents a methodology for determination of a quantitative blood-induced infection residual risk (BIRR) index to be used while evaluating the efficiency of viral security provision in the blood service.

About the authors

V. G. Akimkin

Central Institute of Epidemiology

Email: fake@neicon.ru
ORCID iD: 0000-0003-4228-9044
Moscow, 111123 Russian Federation

A. V. Alimov

Yekaterinburg Research Institute of Viral Infections

Email: fake@neicon.ru
ORCID iD: 0000-0003-0511-9409
Yekaterinburg, 620030

Russian Federation

Yu. A. Zakharova

Yekaterinburg Research Institute of Viral Infections

Author for correspondence.
Email: z.y.alexandrovna@mail.ru
ORCID iD: 0000-0003-3416-0902

Holder of postdoctoral degree in Medicine, Deputy Director for
Science

Yekaterinburg, 620030, 23 Letnya str., Russia

Russian Federation

E. V. Bolgarova

Yekaterinburg Research Institute of Viral Infections

Email: fake@neicon.ru
ORCID iD: 0000-0001-6140-2546
Yekaterinburg, 620030

Russian Federation

M. V. Piterskiy

Yekaterinburg Research Institute of Viral Infections

Email: fake@neicon.ru
ORCID iD: 0000-0001-5506-2389
Yekaterinburg, 620030

Russian Federation

E. I. Sisin

Yekaterinburg Research Institute of Viral Infections

Email: fake@neicon.ru
ORCID iD: 0000-0001-5003-1110
Yekaterinburg, 620030

Russian Federation

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Copyright (c) 2019 Akimkin V.G., Alimov A.V., Zakharova Y.A., Bolgarova E.V., Piterskiy M.V., Sisin E.I.

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