Email this article Antigenic activity of human herpes virus type 8 proteins coding orfK8.1 and orf65
- Issue: Vol 54, No 3 (2009)
- Pages: 45-48
- Section: Articles
- URL: https://virusjour.crie.ru/jour/article/view/11926
- ID: 11926
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Abstract
peptide scanning of the sequences of human herpes virus type 8 (HHV-8) proteins coding orfK8.1 and orf65 was made. The antigenic activity of peptides was evaluated by ELISA. The fragment 101-213 aa of orfK8.1-encoded protein was shown to consist of two sites containing linear B-epitopes that had a weak antigenic activity: 121-145 and 177-209 aa. The protein coding orf65 comprised 2 sites at which linear B-cell epitopes 78-110 aa (a weak antigenic activity) and 142-170 aa (a strong antigenic activity) were located.
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).