Email this article A virological description of serous meningitis in childrenimmunized with vaccine against epidemic parotitis
- Issue: Vol 49, No 5 (2004)
- Pages: 28-32
- Section: Articles
- URL: https://virusjour.crie.ru/jour/article/view/11872
- ID: 11872
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Abstract
The morbidity structure was analyzed in children vaccinated against epidemic parotitis in 1993-2002.
Eight children (4 with serous meningitis and 4 with lesions of the salivary glands) underwent virologic and immunologic
examinations. The molecular typing of the SH-gene fragment of the parotitis virus showed the process in 7 cases
to be provoked by the vaccination strain. Presumedly, progressing vaccine-associated meningitis inhibits antibody formation.
The total incidence of vaccine-associated meningitis was shown, according to Saint Petersburg
data, to be not high, which testifies to a low reactogenicity of the Russian vaccine strain.
Eight children (4 with serous meningitis and 4 with lesions of the salivary glands) underwent virologic and immunologic
examinations. The molecular typing of the SH-gene fragment of the parotitis virus showed the process in 7 cases
to be provoked by the vaccination strain. Presumedly, progressing vaccine-associated meningitis inhibits antibody formation.
The total incidence of vaccine-associated meningitis was shown, according to Saint Petersburg
data, to be not high, which testifies to a low reactogenicity of the Russian vaccine strain.
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References
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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).