Interactions of the hormonal and immunological impairments in males with herpetic keratitis
- Issue: Vol 49, No 2 (2004)
- Pages: 30-32
- Section: Articles
- Submitted: 09.06.2023
- Published: 15.04.2004
- URL: https://virusjour.crie.ru/jour/article/view/11839
- ID: 11839
Cite item
Full Text
Abstract
Data are described in the paper on the significance of hormonal and immunological impairments and on their interrelation within the pathogenesis of herpetic keratitis in males. An evaluation of contents of testosterone, Cortisol, CD8*, CD95*lymphocytes, interleukin-6 and tumor necrosis factor-a (TNF-a) as well as definition of interrelations between them has a prognostic value for males with herpetic keratitis. A dropping concentration of testosterone as observed in males with severe herpetic keratitis is indicative of the feasibility to add some hormonecorrecting drugs to the combined therapy.
References
- Носик Н. Н. Цитокины при вирусных инфекциях // Вопр. вирусол. - 2000. - № 1. - С. 4-10.
- Пинегин Б. В., Минкина Г. Н., Агикова Л. А. и др. Использование нового иммуномодулятора ГМДП при лечении больных папилломавирусной инфекцией шейки матки // Иммунология. - 1997. - № 1. - С. 49-51.
- Рудзит Э. А., Лисица Л. И. Инфекционный процесс и половые гормоны // Пат. физиол. - 1978. - № 6. - С. 77- 83.
- Хаитов Р. М., Игнатьева Г. А., Сидорович И. Г. Иммунология. - М., 2000.
- Цырлова И. Г. Влияние стероидных гормонов на отдельные этапы иммуногенеза: Автореф. дис. ... канд. мед. наук. - Новосибирск, 1977.
- Ahmed S. A., Pounhale W. J., Talal N. Sex hormones, immune responses, and autoimmune diseases: Mechanisms of set hormone action // Am. J. Pathol. - 1985. - Vol. 121, N 3. - P. 531-551.
- Di Piro J. T. Cytokine network with infection Mycobacterial infections, leishmaniosis, human immunodeficiency virus infection, and sepsis // Pharmacotherapy. - 1997. - Vol. 17, N 2. - P. 205-223.
- Ferrando S. J., Rabkin J. G., Poretsky L. Dehydroepiandrosterone sulfate (DHEAS) and testosterone: relation to HIV illness stage and progression over one year // J. Acquir. Immune Defic. Syndr. - 1999. - Vol. 22, N 2. - P. 146-154.
- Han X., Lundberg P., Tanamachi B. et al. Gender influences herpes simplex virus type 1 infection in normal and gamma interferon - mutant mice // J. Virol. - 2001. - Vol. 75, N 6. - P. 3048-3952.
- Hoshino Y., Nagata Y., Gatanaga H. et al. Cytomegalovirus (CMV) retinitis and CMV antigenemia as a clue to impaired adrenocortical function in patients with AIDS //AIDS. - 1997. - Vol. 11, N 14. - P. 1719-1724.
- Schifitto G., McDermott M. P., Evans T. et al. Autonomic performance and dehydroepiandrosterone sulfate levels in H1V-1infected individuals: relationship to TH1 and TH2 cytokine profile // Arch.l Neurol. - 2000. - Vol. 7,N 7. - P. 1027-1032.