Diagnostic advantages of the test system "DS-EIA-HBsAg-0.01" for detection of HBV surface antigen


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Abstract

The new highly sensitive test system "DS-EIA-HBsAg-0.01" (Priority Certificate No. 2006129019 of August 10, 2006) in detecting hepatitis B surface antigen (HBsAg) was assessed. The sensitivity of the test was estimated using the federal standards sample HBsAg 42-28-311-06, panels' samples Boston Biomedica Inc. (West Bridgewater, Mass, USA) and ZeptoMetrix Corp. (Buffalo, NY, USA). The findings have indicated that "DS-EIA-HBsAg-0.01" is equally effective in detecting different subtypes of HBsAg during a seroconversion period earlier than alternative assays. Along with its high analytical and diagnostic sensitivity, the system shows a high diagnostic specificity.

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Copyright (c) 2009 Egorova N.I., Pyrenkova I.Y., Igolkina S.N., Sharipova I.N., Puzyrev V.F., Obryadina A.P., Burkov A.N., Kornienko N.V., Howard A.F., Korovkin A.S., Shalunova N.V., Bektimirov T.A., Kuznetsov K.V., Koshcheeva N.A., Ulanova T.I., Yegorova N.I., Pyrenkova I.Y., Igolkina S.N., Sharipova I.N., Puzyrev V.F., Obryadina A.P., Burkov A.N., Kornienko N.V., Fields H.A., Korovkin A.S., Shalunova N.V., Bektimirov T.A., Kuznetsov K.V., Koshcheyeva N.A., Ulanova T.I.

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