Email this article Diagnostic advantages of the test system "DS-EIA-HBsAg-0.01" for detection of HBV surface antigen
- Issue: Vol 54, No 2 (2009)
- Pages: 44-47
- Section: Articles
- URL: https://virusjour.crie.ru/jour/article/view/11909
- ID: 11909
Cite item
Full Text
Abstract
The new highly sensitive test system "DS-EIA-HBsAg-0.01" (Priority Certificate No. 2006129019 of August 10, 2006) in detecting hepatitis B surface antigen (HBsAg) was assessed. The sensitivity of the test was estimated using the federal standards sample HBsAg 42-28-311-06, panels' samples Boston Biomedica Inc. (West Bridgewater, Mass, USA) and ZeptoMetrix Corp. (Buffalo, NY, USA). The findings have indicated that "DS-EIA-HBsAg-0.01" is equally effective in detecting different subtypes of HBsAg during a seroconversion period earlier than alternative assays. Along with its high analytical and diagnostic sensitivity, the system shows a high diagnostic specificity.
Keywords
References
- Hofer M., Joller-Jemelka H. I., Grob P. J. et al. Frequent chronic hepatitis B virus infection in HIV-infected patients positive for antibody to hepatitis B core antigen only. Swiss HIV Cohort Study // Eur. J. Clin. Microbiol. Infect. Dis. - 1998. - Vol. 17. - P. 6-13.
- Liang T. J., Blum H. E., Wands J. R. Characterization and biological properties of a hepatitis B virus isolated from a patient without hepatitis B virus serological markers // Hepatology. - 1990. - Vol. 12. - P. 204-212.
- Schuttler C. G., Fiedler N., Schmidt K. et al. Suppression of hepatitis B virus enhancer 1 and 2 by hepatitis C virus core protein // J. Hepatol. - 2002. - Vol. 37. - P. 855-862.
- Thiers V., Nakajima E., Kremsdorf D. et al. A transmission of hepatitis B from hepatitis-B-seronegative subjects // Lancet. - 1988. - Vol. 2. - P. 1273-1276.
- Wagner A. A., Loustaud-Ratti V., Chemin I. et al. Double hepatitis B virus infection in a patient with HIV/hepatitis C virus coinfection and "anti-HBc alone" as serological pattern // Eur. J. Clin. Microbiol. Infect. Dis. - 2005. - Vol. 24. - P. 623-627.
- Weinberger K. M., Bauer T., Bohm S., Jilg W. High genetic variability of the group-specific a-determinant of hepatitis B virus surface antigen (HbsAg) and the corresponding fragment of the viral polymerase in chronic virus carriers lacking detectable HbsAg in serum // J. Gen. Virol. - 2000. - Vol. 81. - P. 1165-1174.
Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).