Zika fever immunodiagnostics: overview of test systems

Cover Page

Cite item

Abstract

The threat of rapid spread of Zika virus beyond endemic regions has given rise to more research in field of epidemiology and clinic, as well as to the search for Zika fiver new diagnostic and preventive tools. Between 2013 and 2017 in Russia 18 cases of infection transmission by travellers were reported. Fever Zika reference monitoring center in Volgograd Research Anti-Plague Institute (Volgograd, Russian Federation) provides counseling and methodological assistance on laboratory diagnosis and monitoring of Zika fever. In this regard, a literature review of commercial test systems for immunodiagnostics of this infection was performed. Currently, a number of test systems for solid-phase enzyme-linked immunoassay method (ELISA), immunochromatography and indirect immunofluorescent method (IIFT) have been developed for immunodiagnostics of Zika fever. Euroimmun Ltd. remains the only manufacturer that has access to detailed information on validation of the specificity of the produced diagnostic kits. Independent studies confirm that Euroimmun test systems have high specificity and high sensitivity, which is proved by the study of the material from various populations, including Europeans travelling to Zika virus endemic regions and people residing in these regions. A detailed overview of characteristics of Euroimmun test systems for immunodiagnostics of Zika fever allows us to conclude that there is a rationale for the use of these test systems for Russian Federation sanitary protection by identification of antibodies in patients, presumably infected with the Zika virus.

About the authors

Т. V. Zamarina

Volgograd Research Anti-Plague Institute

Author for correspondence.
Email: vari2@sprint-v.com.ru
ORCID iD: 0000-0002-2965-0555

Tatyana V. Zamarina - Senior fellow in the Laboratory of immudiagnostics.

Volgograd, 400131.

Russian Federation

N. P. Khrapova

Volgograd Research Anti-Plague Institute

Email: fake@neicon.ru
ORCID iD: 0000-0002-9782-6866

Volgograd, 400131.

Russian Federation

E. V. Pimenova

Volgograd Research Anti-Plague Institute

Email: fake@neicon.ru
ORCID iD: 0000-0002-8632-203X

Volgograd, 400131.

Russian Federation

E. I. Khanani

Volgograd Research Anti-Plague Institute

Email: fake@neicon.ru
ORCID iD: 0000-0002-1994-9350

Volgograd, 400131.

Russian Federation

D. V. Viktorov

Volgograd Research Anti-Plague Institute

Email: fake@neicon.ru
ORCID iD: 0000-0002-2722-7948

Volgograd, 400131.

Russian Federation

A. V. Toporkov

Volgograd Research Anti-Plague Institute

Email: fake@neicon.ru
ORCID iD: 0000-0002-3449-4657

Volgograd, 400131.

Russian Federation

References

  1. Попова А.Ю., Топорков А.В., ред. Лихорадка Зика: эпидемиология, клиника, лабораторная диагностика и меры профилактики: Практическое руководство. Волгоград: Волга-Пресс; 2016.
  2. Карань Л.С. Молекулярные методы в диагностике ряда инфекционных заболеваний: традиции и инновации. Available at: https://docplayer.ru/68301036-Molekulyarnye-metody-v-diagnostike-ryada-infekcionnyh-zabolevaniy-tradicii-i-innovacii-karan-l-s-fbun-cnii-epidemiologii-2017.html
  3. Попова А.Ю., Ежлова Е.Б., Демина Ю.В., Топорков А.В., Викторов Д.В., Смелянский В.П. и др. Лихорадка Зика: состояние проблемы на современном этапе. Проблемы особо опасных инфекций. 2016; (1): 5-12. Doi: https://doi.org/10.21055/0370-1069-2016-1-5-12
  4. Centers for Disease Control and Prevention. Diagnostic Tests for Zika Virus. Available at: https://www.cdc.gov/zika/hc-providers/types-of-tests.html
  5. Charrel R., Leparc-Goffart I., Pas S., de Lamballerie X., Koopmans M., Reusken C. State of knowledge on Zika virus for an adequate laboratory response. Available at: https://www.researchgate.net/publication/293950559_State_of_knowledge_on_Zika_virus_for_an_adequate_laboratory_response
  6. Calleri G., Burdino E., Bonora S., Raso R. Zika virus infection in two travelers returning from an epidemic area to Italy, 2016: Algorithm for diagnosis and recommendations. Travel Med. Infect. Dis. 2016; 14(5): 506-8. Doi: https://doi.org/10.1016/j.tmaid.2016.07.001
  7. Charrel R., Leparc-Goffart I., Pas S., de Lamballerie X., Koopmans M., Reusken C. Background review for diagnostic test development for Zika virus infection. Bull. World Health Organ. 2016; 94(8): 574-84. Doi: https://doi.org/10.2471/BLT.16.171207
  8. Zika virus infections. Euroimmun test systems for the diagnosis of Zika virus infections. Available at: http://www.euroimmun.com/documents/Indications/Infections/Zika-virus/HI_2668_I_UK_B.pdf
  9. Huzly D., Hanselmann I., Schmidt-Chanasit J., Panning M. High specificity of a novel Zika virus ELISA in European patients after exposure to different flaviviruses. Euro Surveill. 2016; 21(16). Doi: http://dx.doi.org/10.2807/1560-7917.ES.2016.21.16.30203
  10. Borena W., Hofer T., Stiasny K., Aberle S.W., Gaber M., von Laer D., et al. No molecular or serological evidence of Zikavirus infection among healthy blood donors living in or travelling to regions where Aedes albopictus circulates. PLoS One. 2017; 12(5): e0178175. Doi: http://dx.doi.org/10.1371/journal.pone.0178175
  11. Lanciotti R.S., Kosoy O.L., Laven J.J., Velez J.O., Lambert A.J., Johnson A.J., et al. Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007. Emerg. Infect. Dis. 2008; 14(8): 1232-9. Doi: http://dx.doi.org/10.3201/eid1408.080287
  12. Serological diagnosis of Zika virus infections. Press release. Luebeck, Germany: Euroimmun; 2016. Available at: https://www.euroimmun.com/index.php?eID=dumpFile&t=f&f=3013&token=6cc0bb2eb7c10f484ae50ad91e69cd6424088529
  13. Steinhagen K., Probst C., Radzimski C., Schmidt-Chanasit J., Emmerich P., van Esbroeck M., et al. Serodiagnosis of Zika virus (ZIKV) infections by a novel NS1-based ELISA devoid of cross-reactivity with dengue virus antibodies: a multicohort study of assay performance, 2015 to 2016. Euro Surveill. 2016; 21(50). Doi: http://dx.doi.org/10.2807/1560-7917.ES.2016.21.50.30426
  14. Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека. О желтой лихорадке в Нигерии. Available at: http://www.rospotrebnadzor.ru/about/info/news/news_details.php?ELEMENT_ID=10281
  15. Управление Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека по городу Москве. Профилактика желтой лихорадки. Available at: http://77.rospotrebnadzor.ru/index.php/san-epid/40-2009-08-20-06-08-14/4872-2017-01-26-14-41-59

Copyright (c) 2019 Zamarina Т.V., Khrapova N.P., Pimenova E.V., Khanani E.I., Viktorov D.V., Toporkov A.V.

Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС77-77676 от 29.01.2020.


This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies