Email this article The comparative analysis of wild measles viruses strains isolated in the European Part of the Russian Federation
- Issue: Vol 48, No 4 (2003)
- Pages: 29-35
- Section: Articles
- URL: https://virusjour.crie.ru/jour/article/view/11790
- ID: 11790
Cite item
Full Text
Abstract
Eleven wild measles virus isolated, in 1988 and in 1999-2001 in the European territory of the Russian Federation, were investigated. On the basis of an analysis of N-gene region sequences, encoding the COOH terminal end of nucleoprotein, the isolates were divided into 2 subgroups. According to the WHO classification, subgroup 1 was in line with genotype A and subgroup 2 - with genotype D. Subgroup 2 was close to genotype D4 but differed from it according to its composition of nucleotides on the average by 2.8%, and according to its amino-acid composition - by 2.6%. with respect to the WHO criteria, the latter can be referred to prelimarily as an independent genotype. Finally, the measles viruses' strains of genetic groups A and D circulated in the Russian Federation in 1988, and in 1999-2001.
Keywords
References
- Лазикова Г. Ф. Проблемы ликвидации кори в Российской Федерации // Эпидемиол. и вакцинопрофилактика. - 2002. - № 2. - С. 8-9.
- Маркушин С. Г., Коптяева И. Б., Бурчик М. А., Рота П. Генетический анализ диких штаммов вируса кори, циркулирующих в России в 2000-2001 гг. // Материалы VIII съезда Всероссийского общества эпидемиологов, микробиологов и паразитологов. - М., 2002. - Т. 3. - С. 299-300.
- Chomczynski P. A. Reagents for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples // Biotechniuqes. - 1993. - Vol. 15, N 3. - P. 532-534; 536-537.
- Heider A., Santibanez S., Tischer A. et al. Comparative investigation of long noncoding M-F genome region of wild-type and vaccine measles viruses // Arch. Virol. - 1997. - Vol. 142. - P. 2521-2528.
- Santibanez S., Heider A., Gerike E. et al. Genotyping of measles virus isolates from Central Europe and Russia // J. Med. Virol. - 1999. - Vol. 58, N 3. - P. 313-320.
- World Health Organization. Measles. Nomenclature for describing the genetic characteristics of wild-type measles viruses // Wkly Epidemiol. Rec. - 2001. - Vol. 76. P. 242-247.
Supplementary files
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).