The comparative analysis of wild measles viruses strains isolated in the European Part of the Russian Federation
- Issue: Vol 48, No 4 (2003)
- Pages: 29-35
- Section: Articles
- Submitted: 09.06.2023
- Published: 15.08.2003
- URL: https://virusjour.crie.ru/jour/article/view/11790
- ID: 11790
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Abstract
Eleven wild measles virus isolated, in 1988 and in 1999-2001 in the European territory of the Russian Federation, were investigated. On the basis of an analysis of N-gene region sequences, encoding the COOH terminal end of nucleoprotein, the isolates were divided into 2 subgroups. According to the WHO classification, subgroup 1 was in line with genotype A and subgroup 2 - with genotype D. Subgroup 2 was close to genotype D4 but differed from it according to its composition of nucleotides on the average by 2.8%, and according to its amino-acid composition - by 2.6%. with respect to the WHO criteria, the latter can be referred to prelimarily as an independent genotype. Finally, the measles viruses' strains of genetic groups A and D circulated in the Russian Federation in 1988, and in 1999-2001.
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References
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