Problems of VirologyProblems of VirologyВопросы вирусологии0507-40882411-2097Central Research Institute for Epidemiology55910.36233/0507-4088-78REVIEWSОБЗОРЫAnimal delta-like viruses (Kolmioviridae: Deltavirus) and the origin of the human hepatitis D virus (HDV)Дельта-подобные вирусы (Kolmioviridae: Deltavirus) животных и происхождение вируса гепатита D (hepatitis D virus) человекаhttps://orcid.org/0000-0002-2656-3667IsaevaO. V.ИсаеваО. В.
Russian Federation

Ol’ga V. Isaeva, Ph.D. (Biol.), Lead Researcher of the Viral Hepatitis Laboratory; Lead Researcher of the Molecular and Personalized Medicine Research Institute

105064, Moscow, Russia

125993, Moscow, Russia

Исаева Ольга Владиславовна, канд. биол. наук, ведущий научный сотрудник научно-исследовательского института молекулярной и персонализированной медицины; ведущий научный сотрудник лаборатории вирусных гепатитов

105064, Москва, Россия

125993, Москва, Россия

isaeva.06@mail.ruhttps://orcid.org/0000-0002-3599-117XKyuregyanK. K.КюрегянК. К.
Russian Federation

105064, Moscow, Russia

125993, Moscow, Russia

105064, Москва, Россия

125993, Москва, Россия

https://orcid.org/0000-0002-6636-6801MikhailovM. I.МихайловМ. И.
Russian Federation

105064, Moscow, Russia

125993, Moscow, Russia

105064, Москва, Россия

125993, Москва, Россия

FSBSI «I.I. Mechnikov Research Institute of Vaccines and Sera»ФГБНУ «Научно-исследовательский институт вакцин и сывороток им. И.И. Мечникова»FSBEI FPE «Russian Medical Academy of Continuous Professional Education» of the Ministry of Health of RussiaФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России041120216653403450411202104112021Copyright ©; 2021, Isaeva O.V., Kyuregyan K.K., Mikhailov M.I.Copyright ©; 2021, Исаева О.В., Кюрегян К.К., Михайлов М.И.2021Isaeva O.V., Kyuregyan K.K., Mikhailov M.I.Исаева О.В., Кюрегян К.К., Михайлов М.И.https://creativecommons.org/licenses/by/4.0https://virusjour.crie.ru/jour/article/view/559

Hepatitis D (delta, δ) virus (HDV) was discovered more than 40 years ago, but the understanding of its origin and evolution is poor. This is mainly due to the lack, until recently, of data on the existence of any viruses similar to HDV. The discovery in recent years of sequences of new delta-like agents in a wide range of vertebrate (Vertebrata) and invertebrate (Invertebrata) species has facilitated a revision of views on the origin of HDV and contributed to understanding the place of this unique virus among other animals’ viral agents. The purpose of this review is to analyze the latest published data on new delta-like agents and their biological characteristics.

Вирус гепатита D (дельта, δ) (hepatitis D virus, HDV) открыт более 40 лет назад, однако представления о его происхождении и эволюции крайне ограничены. Причиной этому служило отсутствие до недавнего времени данных о существовании каких-либо вирусов, подобных HDV. Обнаружение в последние годы последовательностей новых дельта-подобных вирусов у широкого спектра представителей позвоночных (Vertebrata) и беспозвоночных (Invertebrata) позволило пересмотреть взгляды на возникновение HDV и способствовало пониманию места этого уникального вируса среди зоонозных инфекционных агентов вирусной природы. Целью данного обзора является анализ недавно опубликованных исследований, посвящённых новым дельта-подобным вирусам и их биологической характеристике.

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