Problems of VirologyProblems of VirologyВопросы вирусологии0507-40882411-2097Central Research Institute for Epidemiology1665010.36233/0507-4088-238njrkwuREVIEWSОБЗОРЫReview ArticleComparative analysis of the taxonomic classification criteria for a number of groups of pathogenic DNA and RNA viruses based on genomic dataСравнительный анализ критериев классификации ряда групп патогенных ДНК- и РНК-содержащих вирусов на основе геномных данныхhttps://orcid.org/0000-0002-1817-0126SizikovaTatiana E.СизиковаТатьяна Евгеньевна
Russian Federation

PhD in Biology

канд. биол. наук, старший научный сотрудник

48cnii@mil.ruhttps://orcid.org/0000-0002-6552-4599LebedevVitaliy N.ЛебедевВиталий Николаевич
Russian Federation

D. Sc. in Biology, Professor, Leading Researcher

д-р биол. наук, профессор, ведущий научный сотрудник

48cnii@mil.ruhttps://orcid.org/0000-0002-6742-3919BorisevichSergey V.БорисевичСергей Владимирович
Russian Federation

D. Sc. in Biology, Professor, Academician of the Russian Academy of Sciences, Head of the Institute

д-р биол. наук, профессор, академик РАН РФ, начальник института

48cnii@mil.ru48th Central Scientific Research Institute of the Ministry of Defense of the Russian FederationФГБУ «48 Центральный научно-исследовательский институт» Минобороны России0507202469320321806062024Copyright ©; 2024, Sizikova T.E., Lebedev V.N., Borisevich S.V.Copyright ©; 2024, Сизикова Т.Е., Лебедев В.Н., Борисевич С.В.2024Sizikova T.E., Lebedev V.N., Borisevich S.V.Сизикова Т.Е., Лебедев В.Н., Борисевич С.В.https://creativecommons.org/licenses/by/4.0https://virusjour.crie.ru/jour/article/view/16650

The basis for criteria of the taxonomic classification of DNA and RNA viruses based on data of the genomic sequencing are viewed in this review. The genomic sequences of viruses, which have genome represented by double-stranded DNA (orthopoxviruses as example), positive-sense single-stranded RNA (alphaviruses and flaviviruses as example), non-segmented negative-sense single-stranded RNA (filoviruses as example), segmented negative-sense single-stranded RNA (arenaviruses and phleboviruses as example) are analyzed. The levels of genetic variability that determine the assignment of compared viruses to taxa of various orders are established for each group of viruses.

В обзоре рассмотрено обоснование критериев идентификации таксономической принадлежности некоторых групп патогенных ДНК- и РНК-содержащих вирусов на основе результатов секвенирования генома. Проанализированы данные секвенирования геномной нуклеиновой кислоты вирусов, геном которых представлен двухцепочечной ДНК (на примере ортопоксвирусов), одноцепочечной «плюс» РНК (на примере альфавирусов и флавивирусов), одноцепочечной несегментированной «минус» РНК (на примере филовирусов), одноцепочечной сегментированной «минус» РНК (на примере аренавирусов и флебовирусов). Для каждой группы вирусов установлены уровни генетической изменчивости, определяющие отнесение сравниваемых вирусов к таксонам разных порядков.

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