Problems of VirologyProblems of VirologyВопросы вирусологии0507-40882411-2097Central Research Institute for Epidemiology1660310.36233/0507-4088-220hcmnwkSHORT COMMUNICATIONКРАТКИЕ СООБЩЕНИЯShort CommunicationSeroprevalence of herpes simplex virus type 1 (Herpesviridae: Simplexvirus: Human alphaherpesvirus 1) in smokersСеропревалентность вируса простого герпеса 1-го типа (Herpesviridae: Simplexvirus: Human alphaherpesvirus 1) у курильщиковhttps://orcid.org/0000-0002-4799-0879MaysJalil B.MaysJalil Basil
Iraq

Assistant Professor, Principle investigator, Department of Microbiology, College of Medicine

Медицинский колледж, доцент, главный исследователь, кафедра микробиологии

medicalresearch20@yahoo.comMariemMohammed Ali N.
Iraq

Assistant lecturer, Investigator, Department of Microbiology, College of Medicine

Медицинский колледж, ассистент преподавателя, исследователь, кафедра микробиологии

mariem.nbeel@uobasrah.edu.iqeahttps://orcid.org/0000-0003-7884-1224AlabadiHadi I.
Iraq

Physician, Researcher

врач, научный сотрудник

drhadilazim345@gmail.comUniversity of BasrahУниверситет БасрыBasrah Health DirectorateУправление здравоохранения Басры0605202469218719219012024Copyright ©; 2024, Mays J.B., Mariem M.N., Alabadi H.I.Copyright ©; 2024, Mays J.B., Mariem M.N., Alabadi H.I.2024Mays J.B., Mariem M.N., Alabadi H.I.Mays J.B., Mariem M.N., Alabadi H.I.https://creativecommons.org/licenses/by/4.0https://virusjour.crie.ru/jour/article/view/16603

Introduction. Herpes simplex virus type 1 (HSV-1) is one of the most common human viral infections and has a double-stranded DNA genome belonging to the Herpesviridae family. Smoking is one of the leading causes of disease and premature death worldwide, responsible for the death of up to six million people annually. The purpose of the current study was to determine the seroprevalence of HSV-1 infection among smokers.‎

Methods. The search strategy was conducted in the period from December 2022 to January 2023. The study included a random sample of 94 (88 males, and 6 females) healthy participants, aged between ≤ 20 to ≥ 60 years, with 50 participants as the control group. The HSV serological testing consisted of detecting antibodies to HSV-1 IgG with the help of ELISA.

Results. Most participants were university students, consisting of 45.7% males and 5.3% females, followed by employed smokers, consisting of 0.2% males and 1.1% females. The number of females was much lower than that of males reaching 6.4 and 93.6% respectively, due to customs and traditions. The seroprevalence was 24.47, 22.3 and 2.1% in males and females respectively. The seroprevalence rate was 13.8% in hookah and cigarette smokers, 9% in cigarette smokers and 1.1% in hookah smokers exclusively. The highest rate was observed in the age groups of 21-30 and 31–40 years with 12.80% and 7.40% respectively.

Conclusions. The study revealed that the seroprevalence of HSV-1 IgG was 24.47%, and was higher among hookah and cigarette smokers compared to those who exclusively smoked cigarettes or hookah.

Введение. Вирус простого герпеса 1-го типа (ВПГ-1) – один из самых распространенных вирусных агентов, инфицирующих человека, имеет геном с двухцепочечной ДНК и относится к семейству Herpesviridae. Курение – одна из основных причин заболеваний и преждевременной смерти во всем мире, от которой ежегодно умирает до 6 млн человек.

Цель настоящего исследования – определение серопревалентности ВПГ-1 среди курильщиков.

Методы. Исследование проводили в период с декабря 2022 г. по январь 2023 г. В исследование была включена случайная выборка из 94 (88 мужчин и 6 женщин) здоровых лиц в возрасте от 20 до 60 лет, 50 участников составили контрольную группу. Серологическое тестирование на ВПГ заключалось в выявлении антител к ВПГ-1 класса IgG с помощью ИФА.

Результаты. Большинство участников были студентами университета – 45,7% мужчин и 5,3% женщин, за ними следовали работающие курильщики – 0,2% мужчин и 1,1% женщин. Число женщин было значительно меньше, чем мужчин, и составило 6,4 и 93,6% соответственно, что объясняется обычаями и традициями. Серопревалентность составила 24,47, 22,3 и 2,1% среди мужчин и женщин соответственно. Уровень серопревалентности составил 13,8% среди курильщиков кальяна и сигарет, 9% исключительно среди курильщиков сигарет и 1,1% исключительно среди курильщиков кальяна. Наибольший уровень выявляемости антител наблюдался в возрастных группах 21–30 и 31–40 лет – 12,80 и 7,40% соответственно.

Заключение. Исследование показало, что серопревалентность ВПГ-1 IgG составила 24,47% и была выше среди курильщиков кальяна и сигарет по сравнению с теми, кто курил исключительно сигареты или кальян.

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