Problems of VirologyProblems of VirologyВопросы вирусологии0507-40882411-2097Central Research Institute for Epidemiology12277ArticlesСтатьиResearch ArticleMumps vaccine virus transmissionТрансмиссия вакцинных штаммов вируса паротита15122013586VOL 58, NO6 (2013)ТОМ 58, №6 (2013)424509062023Copyright ©; 2013, Atrasheuskaya A.V., Kulak M.V., Atrasheuskaya A.V., Karpov I.A., Fisenko E.G., Ignatyev G.M.Copyright ©; 2013, Отрашевская Е.В., Кулак М.В., Отрашевская А.В., Карпов И.А., Фисенко Е.Г., Игнатьев Г.М.2013Atrasheuskaya A.V., Kulak M.V., Atrasheuskaya A.V., Karpov I.A., Fisenko E.G., Ignatyev G.M.Отрашевская Е.В., Кулак М.В., Отрашевская А.В., Карпов И.А., Фисенко Е.Г., Игнатьев Г.М.https://creativecommons.org/licenses/by/4.0https://virusjour.crie.ru/jour/article/view/12277

In this work we report the mumps vaccine virus shedding based on the laboratory confirmed cases of the mumps virus (MuV) infection. The likely epidemiological sources of the transmitted mumps virus were children who were recently vaccinated with the mumps vaccine containing Leningrad-Zagreb or Leningrad-3 MuV. The etiology of the described cases of the horizontal transmission of both mumps vaccine viruses was confirmed by PCR with the sequential restriction analysis.

Проведено эпидемиологическое и лабораторное исследование случаев передачи вакцинных штаммов вируса паротита (ВП). Наиболее вероятным источником ВП в домашних очагах были дети, впервые привитые вакцинами, содержащими штаммы ВП Ленинград-Загреб и Ленинград-3. Все случаи передачи вакцинного штамма ВП были лабораторно подтверждены методом ОТ-ПЦР с последующим рестрикционным анализом.

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