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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Problems of Virology</journal-id><journal-title-group><journal-title xml:lang="en">Problems of Virology</journal-title><trans-title-group xml:lang="ru"><trans-title>Вопросы вирусологии</trans-title></trans-title-group></journal-title-group><issn publication-format="print">0507-4088</issn><issn publication-format="electronic">2411-2097</issn><publisher><publisher-name xml:lang="en">Central Research Institute for Epidemiology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">12165</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Molecular-Genetic Analysis of the Field Isolates of Avian Leucosis Viruses in the Russian Federation</article-title><trans-title-group xml:lang="ru"><trans-title>Молекулярно-генетический анализ полевых изолятов вируса лейкоза птиц, циркулирующих на территории Российской Федерации</trans-title></trans-title-group></title-group><pub-date date-type="pub" iso-8601-date="2012-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2012</year></pub-date><volume>57</volume><issue>5</issue><issue-title xml:lang="en">VOL 57, NO5 (2012)</issue-title><issue-title xml:lang="ru">ТОМ 57, №5 (2012)</issue-title><fpage>38</fpage><lpage>43</lpage><history><date date-type="received" iso-8601-date="2023-06-09"><day>09</day><month>06</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2012, Plotnikov V.A., Grebennikova T.V., Yuzhakov A.G., Dudnikova E.K., Norkina S.N., Zaberezhny A.D., Aliper T.I., Fadly A.M.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2012, Плотников В.А., Гребенникова Т.В., Южаков А.Г., Дудникова Е.К., Норкина С.Н., Забережный А.Д., Алипер Т.И., Fadly A.M.</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="en">Plotnikov V.A., Grebennikova T.V., Yuzhakov A.G., Dudnikova E.K., Norkina S.N., Zaberezhny A.D., Aliper T.I., Fadly A.M.</copyright-holder><copyright-holder xml:lang="ru">Плотников В.А., Гребенникова Т.В., Южаков А.Г., Дудникова Е.К., Норкина С.Н., Забережный А.Д., Алипер Т.И., Fadly A.M.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://virusjour.crie.ru/jour/article/view/12165">https://virusjour.crie.ru/jour/article/view/12165</self-uri><abstract xml:lang="en"><p>Results of monitoring of different subtypes of avian leukosis virus (ALV) from commercial poultry farms in 14 regions of Russian Federation were discussed. Only three regions were found to be negative. ALV was detected in other 11 regions in 46-64% cases (for different regions). The phylogenetic analysis of the genomes for the 12 field isolates of ALV was carried out in different regions of Russian Federation. The isolates belong to different subtypes of the virus and form two large groups. The genomic differences between Russian and foreign isolates within each group range from 5% to 10%.</p></abstract><trans-abstract xml:lang="ru"><p>Приведены результаты мониторинга вируса лейкоза птиц различных генотипов в коммерческих птицеводческих хозяйствах 14 регионов Российской Федерации. Только в трех областях вирус лейкоза птиц не был обнаружен. В остальных 11 областях вирус выявляли в 46-64% случаев. Проведен филогенетический анализ генома 12 полевых изолятов вируса лейкоза птиц, циркулирующих в коммерческих птицеводческих хозяйствах различных регионов РФ. Выделенные изоляты относятся к различным подтипам вируса и формируют 2 обширные группы. геномные различия между российскими и зарубежными изолятами внутри соответствующих групп составляют от 5 до 10%.</p></trans-abstract><kwd-group xml:lang="en"><kwd>avian leucosis virus</kwd><kwd>retroviruses</kwd><kwd>polymerase chain reaction</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>вирус лейкоза птиц</kwd><kwd>ретровирусы</kwd><kwd>полимеразная цепная реакция</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Гребенникова Т. В., Алексеев К. П., Власова А. Н. и др. Исследование поголовья птиц на наличие вируса птичьего лейкоза методом ПЦР. Птицы и птицепродукты. 2003; 6: 35-37.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Плотников В. А., Алипер Т. И., Дудникова Е. К. и др. Распространение вируса лейкоза птиц на территории Российской Федерации. В кн.: 10-й Международный конгресс «Здоровье и образование в XXI веке». Инновационные технологии в биологии и медицине.М.: РУДН; 2009.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Плотников В. А., Алипер Т. И., Дудникова Е. К. и др. Филогенетический анализ изолятов вируса лейкоза птиц, циркулирующих на территории Российской Федерации. В кн.: VI Международный ветеринарный конгресс по птицеводству. М.; 2010. 44-48.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Bacon L. D., Witter R. L., Fadly A. Augmentation of retrovirus-induced lymphoid leukosis by Marek’s disease herpesviruses in white leghorn chickens. J. Virol. 1989; 63: 504-512.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Bacon L. D., Hunt H. D., Cheng H. H. Genetic resistance to Marek’s disease. In: Hirai K., ed. Current topics in microbiology and immunology. New York: Springer-Verlag; 2001; 255: 121-141.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Blanca L., Hunt H., Silva R., Fadly A. Identification and characterization of subgroup J avian leukosis viruses (ALV) expressing subgroup A ALV envelope. Virology 2000; 276: 37-43.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Coffin J. M. Structure and classification of retroviruses. In: Levy J. A. ed. The Retroviridae. New York: Plenum Press; 1992; 1: 19-49.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Fadly A. M., Smith E. J. Isolation and some characteristics of a subgroup J-like avian leukosis virus associated with myeloid leukosis in meat-type chickens in the United States. Avian Dis. 1999; 43: 391-400.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Fadly A. M. Isolation and identiication of avian loeukosis viruses: a review. Avian Pathol. 2000; 29: 529-535.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Fadly A.M., Payne L. N. Leukosis/sarcoma group. In: Saif Y. M. et al. eds. Diseases of Poultry. 11th ed. Anes: Iowa State Press, 2003; 465-516.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Fadly A. M. Silva R., Hunt H. et al. Isolation and characterization of an adventitious avian leukosis virus isolated from commercial Marek’s disease vaccines. Avian Dis. 2006; 50: 380-385.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Gingerich E., Porter R. E., Lupiani B., Fadly A. M. Diagnosis of myeloid leukosis induced by a recombinant avian leukosis virus in commercial white leghorn egg laying flocks. Avian Dis. 2002; 46: 745-748.</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Lee L. F., Fadly A. M., Hunt H. D. Avian leukosis virus subgroup J envelope gene product for diagnosis and immunogenic composition. USA. Pat. 6,146,641.</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Pandiri A. R., Mays J. K., Fadly A. M.Influence of strain, dose, of virus, and age of inoculation on subgroup J avian leucosis virus persistence, antibody response and oncogenicity in commercial meat-type chickens. Avian Dis. 2007; 51: 725-732.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Pandir A. R., Gimeno I. M., Reed W. M. et al. Distribution of viral antigen gp85 and provirus in various tissues from commercial meat-type and experimental White Leghorn Line 0 chickens with different subgroup J avian leucosis infection profiles. Avian Patol. 2008; 37 (1): 7-13.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Payne L. N., Brown S. R., Bumstead N. et al. A novel subgroup of exogenous avian leukosis virus in chickens. J. Gen. Virol. 1991; 72: 801-807.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Payne L. N., Howes K., Smith L. M., Venugopal K. Current status of diagnosis, epidemiology and control of ALV-J. In: Fadly A. M. et al. eds. Avian Tumor Viruses Symposium. Reno, NV: American Association of Avian Pathologists. 1997; 58-62.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Silva R. F., Fadly A. M., Hunt H. D. Hypervariability in the envelope genes of subgroup J avian leukosis viruses obtained from different farms in the U. S. Virology. 2000; 272: 106-111.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Silva R. F., Fadly A. M. Evolution of ALV-J strains. In: Kaleta E. F. et al. eds.,.International Symposium on ALV-J and Other Avian Retroviruses. Rauischholzhausen, Germany: World Veterinary Poultry Association, 2000:23-31.</mixed-citation></ref><ref id="B20"><label>20.</label><mixed-citation>Smith E. J., Fadly A. M., Crittenden L. B. Observations on an enzyme-linked immunosorbent assay for the detection of antibodies against avian leukosis/sarcoma viruses. Avian Dis. 1986; 30: 488-493.</mixed-citation></ref><ref id="B21"><label>21.</label><mixed-citation>Smith E. J., Salter D. W., Silva R. F., Crittenden L. B. Selective shedding and congenital transmission of endogenous avian leukosis viruses. J. Virol. 1986; 60: 1050-1054.</mixed-citation></ref><ref id="B22"><label>22.</label><mixed-citation>Thapa B. R., Omar A. R., Arshad S. S., Hair-Bejo M. Detection of avian leukosis virus subgroup J in chicken flocks from Malaysia and their molecular characterization. Avian Pathol. 2004; 33 (3): 359-363.</mixed-citation></ref><ref id="B23"><label>23.</label><mixed-citation>Witter R. L., Lee L. F., W. Okazaki W. Expression of endogenous (gs, chick helper factor, Rous-associated virus-O) and exogenous avian RNA tumor viruses. J. Natl. Cancer Inst. 1975; 55: 215-218.</mixed-citation></ref><ref id="B24"><label>24.</label><mixed-citation>Witter R. L., Bacon L. D., Hunt H. D. et al. Avian leukosis virus subgroup J infection profiles in broiler breeder chickens: association with virus transmission to progeny. Avian Dis. 2000; 44: 913-931.</mixed-citation></ref><ref id="B25"><label>25.</label><mixed-citation>Zavala G., Cheng S., Jackwood M. W. Molecular epidemiology of avian leukosis virus subgroup J and evolutionary history of its 3’ untranslated region. Avian Dis. 2007; 51 (4): 942-953.</mixed-citation></ref></ref-list></back></article>
