Problems of VirologyProblems of VirologyВопросы вирусологии0507-40882411-2097Central Research Institute for Epidemiology12128ArticlesСтатьиResearch ArticleA new unique HIV-1 recombinant form detected in BelarusНовая уникальная рекомбинантная форма ВИЧ-1, выявленная в Беларуси15062012573VOL 57, NO3 (2012)ТОМ 57, №3 (2012)91409062023Copyright ©; 2012, Eremin V.F., Gasich E.L., Sosinovich S.V.Copyright ©; 2012, Еремин В.Ф., Гасич Е.Л., Сосинович С.В.2012Eremin V.F., Gasich E.L., Sosinovich S.V.Еремин В.Ф., Гасич Е.Л., Сосинович С.В.https://creativecommons.org/licenses/by/4.0https://virusjour.crie.ru/jour/article/view/12128

The paper presents data on the molecular genetic characteristics of a new HIV-1 recombinant form. The study has shown that the virus is referred to as HIV-1 subtype B in terms of the gag gene and HIV-1 subtype A in terms of the pol and env genes. At the same time the new isolate is closer, in terms of the gag gene, to the HIV-1 DQ207943 strain isolated in Georgia, in terms of the pol gene, to the HIV-1 AF413987.1 strain isolated in Ukraine and, in terms of the env gene to the HIV-1 AY500393 strain isolated in Russia. Thus, the described new HIV-1 recombinant form has the following structure: BgagApolAenv The gag, pol, and env gene sequences from the new unique HIV-1 recombinant form have been registered in the international database EMBL/Genbank/DDBJ under accession numbers FR775442.1, FN995656.1, and FR775443.1.

Представлены данные о молекулярно-генетической характеристике новой рекомбинантной формы ВИЧ-1. Как показали проведенные исследования, вирус по гену gag был отнесен к субтипу В, а по генам pol и env - к субтипу А ВИЧ-1. При этом по гену gag новый изолят более близок к грузинскому изоляту ВИЧ-1 DQ207943, по гену pol - к изоляту AF413987.1 из Украины, а по гену env - к AY500393 из России. Таким образом, описанная новая рекомбинантная форма ВИЧ-1 имеет следующую структуру: B gagA polA env. Последовательности новой уникальной рекомбинантной формы ВИЧ-1 по генам gag, pol и env зарегистрированы в международной базе данных EMBL/Genbank/DDBJ под номерами FR775442.1, FN995656.1, FR775443.1.

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